Tesirine (SG3249) 是一种用于抗体偶联药物 (ADC) 的 药物-linker 连接物,能用于多种癌症的研究。PBD Dimer 是一种 DNA 烷化剂,能抑制 DNA 复制。
货号:ajcx35246
CAS:1595275-62-9
分子式:C75H101N9O23
分子量:1496.65
溶解度:DMSO : 200 mg/mL (133.63 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Tesirine (SG3249) is a drug-linker conjugates for ADC which is used in the treatment of several cancers. PBD Dimer is a DNA alkylating which inhibits DNA replication[1].
[1]. Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs. Uppsala Universitet.