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3-Demethylcolchicine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
3-Demethylcolchicine图片
规格:98%
分子量:385.41
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
3-Demethylcolchicine 是秋水仙碱的代谢产物,碳环上有一个羟基参与自由基的清除并且能显著抑制角叉菜胶水肿。
货号:ajcx34426
CAS:7336-33-6
分子式:C21H23NO6
分子量:385.41
溶解度:DMSO : 100 mg/mL (259.46 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

3-Demethylcolchicine, a colchicine metabolite, possesses a hydroxy-group on its carbon ring that could participate in radical scavenging and markedly inhibits the carrageenin edema[1][2].

[1]. Modriansky M, et al. Anti-/pro-oxidant effects of phenolic compounds in cells: are colchicine metabolites chain-breaking antioxidants•. Toxicology. 2002;177(1):105-117.
[2]. Sugio K, et al. Separation of tubulin-binding and anti-inflammatory activity in colchicine analogs and congeners. Life Sci. 1987;40(1):35-39.