Glyco-diosgenin是一种合成的表面活性剂和去污剂，用于从膜中提取蛋白质以进行结构和功能研究，以及对膜蛋白质进行单粒子冷冻电子显微镜(cryoEM)研究。
货号:ajcx30726
CAS:1402423-29-3
分子式:C56H92O25
分子量：1165.31
溶解度:DMSO: 100 mg/mL (85.81 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Glyco-diosgenin is a synthetic surfactant and detergent for extracting proteins from membranes for structure and function studies, and single-particle cryo-electron microscopy (cryoEM) studies of membrane proteins[1][2].

Glyco-diosgenin (16 h) solubilizes and purifies the twin arginine translocation BC (TatBC) complex[1].

[1]. Dalsen L, et, al. In meso crystallogenesis. Compatibility of the lipid cubic phase with the synthetic digitonin analogue, glyco-diosgenin. J Appl Crystallogr. 2020 Mar 25;53(Pt 2):530-535. [2]. Wojnowska M,et, al. Precursor-Receptor Interactions in the Twin Arginine Protein Transport Pathway Probed with a New Receptor Complex Preparation. Biochemistry. 2018 Mar 13;57(10):1663-1671.