Biotin-PEG4-amino-t-Bu-DADPS-C6-azide是一种PROTAClinker，属于PEG类。可用于合成PROTAC分子。
货号:ajcx30282
CAS:1260247-50-4
分子式:C43H67N7O9SSi
分子量：886.18
溶解度:DMSO: 100 mg/mL (112.84 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562