Yuanhuacine(Gnidilatidin)，一种来自Daphnegenkwa的达芙烷二萜，具有广泛的抗肿瘤活性。Yuanhuacine是一种具有口服活性的的DNA损伤剂。
货号:ajcx29784
CAS:60195-70-2
分子式:C37H44O10
分子量：648.74
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Yuanhuacine (Gnidilatidin), a daphnane diterpenoid from the flowers of Daphne genkwa with extensive anti-tumor activity. Yuanhuacine is a DNA-damaging agent with orally active[1][2].

[1]. Ji In Kang, et al. Anti-Tumor Activity of Yuanhuacine by Regulating AMPK/mTOR Signaling Pathway and Actin Cytoskeleton Organization in Non-Small Cell Lung Cancer Cells. PLoS One. 2015 Dec 11;10(12):e0144368. [2]. Ruowen Zhang, et al. The Chinese herb isolate yuanhuacine (YHL-14) induces G2/M arrest in human cancer cells by up-regulating p21 protein expression through an p53 protein-independent cascade. J Biol Chem. 2014 Mar 7;289(10):6394-403.