Potent and selective P2Y14 receptor agonist
货号:ajcx27154
CAS:N/A
分子式:C10H13N2Na3O10P2S
分子量:484.2
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Potent and selective P2Y14 receptor agonist (EC50 = 0.92 nM). Exhibits >2000-fold selectivity over P2Y6.
Das et al (2010) Human P2Y14 receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups J.Med.Chem. 53 471 PMID:19902968 |Lazarowski et al (2015) UDP-sugars as extracellular signaling molecules: cellular and physiologic consequences of P2Y14 receptor activation. Mol.Pharmacol. 88 151 PMID:25829059