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BRL 15572 hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BRL 15572 hydrochloride图片
规格:98%
分子量:443.42
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
BRL 15572 hydrochloride 是 h5-HT1D 的选择性拮抗剂,对 h5-HT1D 受体具有高亲和力。
货号:ajcx26764
CAS:1173022-77-9
分子式:C25H27ClN2O.HCl
分子量:443.42
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:现货

Background:

A selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B, and exhibiting little or no affinity for a range of other receptor types.


Hagan et al (1997) Stimulation of 5-HT1B receptors causes hypothermia in the rat. Eur.J.Pharmacol. 331 169 PMID:9274976 |Price et al (1997) SB-216641 and BRL-15572 - compounds to pharmacologically discriminate h5-HT1B and h5-HT1D receptors. Naunyn Schmiedebergs Arch.Pharmacol. 356 312 PMID:9303567 |Saxena et al (1998) 5-HT1-like receptors: a time to bid goodbye. TiPS 19 311 PMID:9745358 |Schlicker et al (1997) Effects of selective h5-HT1B (SB-216641) and h5-HT1D (BRL-15572) receptor ligands on guinea-pig and human 5-HT auto- and heteroreceptors. Naunyn Schmiedebergs Arch.Pharmacol. 356 321 PMID:9303568