A phase II metabolite of etodolac
货号:ajcx25290
CAS:79541-43-8
分子式:C23H29NO9
分子量:463.5
溶解度:Methanol: soluble
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Etodolac acyl glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor etodolac .1It is formedviaglucuronidation of etodolac by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A9, UGT1A10, and UGT2B7.
1.Kutsuno, Y., Itoh, T., Tukey, R.H., et al.Glucuronidation of drugs and drug-induced toxicity in humanized UDP-glucuronosyltransferase 1 miceDrug Metab. Dispos.42(7)1146-1152(2014)