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Solanesol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Solanesol图片
规格:98%
分子量:631.1
包装与价格:
包装价格(元)
1g电议
5g电议
10g电议
25g电议

产品介绍
茄尼醇是一种脂肪族萜烯醇,主要存在于茄科植物中,具有抗炎、神经保护和抗菌活性。
货号:ajcx23488
CAS:13190-97-1
分子式:C45H74O
分子量:631.1
溶解度:Ethanol: 0.25mg/mL
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Solanesol is a trisesquiterpenoid that has been found inN. tabacumand has diverse biological activities.1,2,3It is active againstE. coli,M. phlei,P. aeruginosa, andS. aureus.1Solanesol (40 µM) increases basal heme oxygenase-1 (HO-1) and nuclear factor erythroid 2-related factor 2 (Nrf2) activities and inhibits LPS-induced production of IL-6, IL-1β, and TNF-α in RAW 264.7 cells.2It reduces escape latency in the Morris water maze and the number of slips in a beam-crossing task in a rat model of Huntington's disease induced by 3-nitropropionic acid when administered at doses of 5, 10, and 15 mg/kg.3Solanesol is also a precursor in the formation of polynuclear aromatic hydrocarbons (PAHs), which are carcinogenic components of tobacco smoke, and has been used as a synthetic intermediate in the synthesis of coenzyme Q10and vitamin K analogs that have antioxidant activities.1


1.Yan, N., Liu, Y., Liu, L., et al.Bioactivities and medicinal value of solanesol and its accumulation, extraction technology, and determination methodsBiomolecules9(8)334(2019) 2.Yao, X., Lu, B., LÜ, C., et al.Solanesol induces the expression of heme oxygenase-1 via p38 and Akt and suppresses the production of proinflammatory cytokines in RAW264.7 cellsFood Funct.8(1)132-141(2017) 3.Mehan, S., Monga, V., Rani, M., et al.Neuroprotective effect of solanesol against 3-nitropropionic acid-induced Huntington's disease-like behavioral, biochemical, and cellular alterations: Restoration of coenzyme-Q10-mediated mitochondrial dysfunctionIndian J. Pharmacol.50(6)309-319(2018)