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Hydroflumethiazide-13C-d2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Hydroflumethiazide-13C-d2图片
包装:1mg
规格:98%
市场价:4074元
分子量:334.3

产品介绍
An internal standard for the quantification of hydroflumethiazide
货号:ajcx22634
CAS:1189877-11-9
分子式:C7[13C]H6D2F3N3O4S2
分子量:334.3
溶解度:DMSO: Soluble,Methanol: Soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Hydroflumethiazide-13C-d2is intended for use as an internal standard for the quantification of hydroflumethiazide by GC- or LC-MS. Hydroflumethiazide is a thiazide diuretic and an inhibitor of carbonic anhydrase (CA).1It is selective for CAII, CAVB, CAVII, CAIX, CAXII, and CAXIV (Kis = 0.24-0.31 µM) over CAI, CAIV, and CAVI (Kis = 2.8-8.3 µM), as well as CAIII, CAVA, and CAXIII (Kis = >10 µM). Formulations containing hydroflumethiazide have been used in the treatment of hypertension.


1.Temperini, C., Cecchi, A., Scozzafava, A., et al.Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adductBioorg. Med. Chem. Lett.18(8)2567-2573(2008)