| 规格: | 98% |
| 分子量: | 462.6 |
| 包装 | 价格(元) |
| 500ug | 电议 |
| 1mg | 电议 |
Background:
1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PE is intended for use as an internal standard for the quantification of 1-palmitoyl-2-hydroxy-sn-glycero-3-PE by GC- or LC-MS. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring lysophospholipid.1It inhibits the growth ofL. donovanipromastigotes (GI50= 8 µM).21-Palmitoyl-2-hydroxy-sn-glycero-3-PE serum levels are decreased in a mouse model of alcohol-induced liver injury and in a hepatocellular carcinoma mouse xenograft model.3Human serum levels are also decreased immediately and 14 hours following an exercise regimen of 2.5 hours of running for three days.11-Palmitoyl-2-hydroxy-sn-glycero-3-PE has been used as an internal standard for the quantification of saturated lysophosphoethanolamines.4
1.Nieman, D.C., Shanely, R.A., Gillitt, N.D., et al.Serum metabolic signatures induced by a three-day intensified exercise period persist after 14 h of recovery in runnersJ. Proteome Res.12(10)4577-4584(2013) 2.Achterberg, V., and Gercken, G.Cytotoxicity of ester and ether lysophospholipids on Leishmania donovani promastigotesMol. Biochem. Parasitol.23(2)117-122(1987) 3.Li, S., Liu, H., Jin, Y., et al.Metabolomics study of alcohol-induced liver injury and hepatocellular carcinoma xenografts in miceJ. Chromatogr. B Analyt. Technol. Biomed. Life Sci.879(24)2369-2375(2011) 4.Avadhani, M., Geyer, R., White, D.C., et al.Lysophosphatidylethanolamine is a substrate for the short-chain alcohol dehydrogenase SocA from Myxococcus xanthusJ. Bacteriol.188(24)8543-8550(2006)
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