A neuropeptide with diverse biological activities
货号:ajcx20916
CAS:N/A
分子式:C13H16O3
分子量：220.3
溶解度:
纯度：98%
存储：Store at -20°C
库存：现货

Background:

CAY10621 is an inhibitor of sphingosine kinase 1 (SPHK1; IC₅₀= 3.3 μM).¹It is selective for SPHK1 over SPHK2 at 10 μM and PKC at concentrations less than 100 μM. CAY10621 inhibits SPHK1 activity by 70% in U937 cells when used at a concentration of 5 μM.

1.Wong, L., Tan, S.L., Lam, Y., et al.Synthesis and evaluation of sphingosine analogues as inhibitors of sphingosine kinasesJournal of Medicinal Chemistry523618-3626(2009)