A neuropeptide with diverse biological activities
货号:ajcx20864
CAS:N/A
分子式:C24H29D11O3
分子量：387.6
溶解度:DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

(±)-CP 55,940-d₁₁is intended for use as an internal standard for the quantification of (±)-CP 55,940 by GC- or LC-MS. (±)-CP 55,940 is a potent, non-selective cannabinoid (CB) receptor agonist (K_is = 5 and 1.8 nM for human CB₁and CB₂, respectively).¹It stimulates [³⁵S]GTPγS binding to rat cerebellar membranes (EC₅₀s = 0.22-0.96 nM).²In vivo, (±)-CP 55,940 induces analgesia in the tail clamp, hot plate, tail flick, flinch jump, and PBQ-induced writhing tests with 50% maximum possible effect (MPE₅₀) values of 0.46, 1.11, 0.55, 0.63, and 0.29 mg/kg, respectively.³(±)-CP 55,940 also decreases the discrimination index (DI) of female, but not male, rats in the object location task as well as the DI of male, but not female, rats in the novel object recognition task.⁴

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