TRAP-6 peptide is a hexapeptide corresponding to residues 42-47 of protease-activated receptor 1 (PAR1).
货号:ajcx19028
CAS:N/A
分子式:C34H56N10O9•XCF3COOH
分子量:748.9
溶解度:DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 1 mg/ml
纯度:98%
存储:Store at -20°C
库存:
现货Background:
TRAP-6 peptide is a hexapeptide corresponding to residues 42-47 of protease-activated receptor 1 (PAR1). It acts as an agonist of PAR1, inducing platelet aggregation in human platelet-rich plasma ex vivo (EC50 = 0.8 µM). TRAP-6 (0.3 and 0.6 mg/kg) has a triphasic effect on mean arterial blood pressure (MAP) in anesthetized rats with a short decrease, an increase, and then a longer decrease in MAP following intravenous administration.