Monohydroxy melphalan is a DNA alkylating agent and a degradation product of melphalan.
货号:ajcx18688
CAS:N/A
分子式:C13H19ClN2O3•2HCl
分子量：359.7
溶解度:DMSO: soluble,Methanol: soluble,Water: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Monohydroxy melphalan is a DNA alkylating agent and a degradation product of melphalan . Monohydroxy melphalan is formed by the hydrolysis of melphalan in aqueous solutions, including cell culture medium and human plasma. It increases the level of DNA adducts in ML-1 myeloblastic leukemia cells in a concentration-dependent manner and induces cytotoxicity with an IC50 value of 28.1 μg/ml.