L-681,217 is an antibiotic originally isolated from S.
货号:ajcx18626
CAS:N/A
分子式:C36H53NO10
分子量：659.8
溶解度:DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

L-681,217 is an antibiotic originally isolated from S. cattleya. It is active against Gram positive and Gram negative bacteria when used at a concentration of 255 µg/ml. L-681,217 inhibits bacterial protein synthesis at the elongation stage, completely inhibiting poly(U)-dependent poly(Phe) synthesis (EC50 = 0.4 µM) and increasing elongation factor Tu (EF-Tu)-associated GTPase activity in E. coli (EC50 = 6 µM). It does not inhibit poly(U)-dependent poly(Phe) synthesis in S. aureus (EC50 = >1,000 µM).