1-Octadecyl lysophosphatidic acid (sodium salt) (1-Octadecyl LPA (sodium salt)) is a LPA analog containing stearyl alcohol at the sn-1 position.
货号:ajcx17826
CAS:N/A
分子式:C21H44O6P•Na
分子量：446.5
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

1-Octadecyl lysophosphatidic acid (sodium salt) (1-Octadecyl LPA (sodium salt)) is a LPA analog containing stearyl alcohol at the sn-1 position. LPA binds to one of five different G protein-linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has platelet aggregating activity with an EC50 value of 9 nM versus an EC50 value of 177 nM for 1-octadecanoyl LPA.