Tigecycline-d9 is intended for use as an internal standard for the quantification of tigecycline by GC- or LC-MS.
货号:ajcx17544
CAS:2699607-86-6
分子式:C29H30D9N5O8
分子量：594.7
溶解度:DMSO: Slightly Soluble,Methanol: Slightly Soluble,Water: Slightly Soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Tigecycline-d9 is intended for use as an internal standard for the quantification of tigecycline by GC- or LC-MS. Tigecycline is a broad-spectrum glycylcycline antibiotic that binds to the bacterial 30S ribosome, blocking the entry of transfer RNA, which halts protein synthesis and inhibits bacterial growth. It is active against a panel of 1,924 European clinical bacterial isolates including S. aureus, S. epidermidis, S. pneumoniae, E. faecalis, E. faecium, E. coli, K. pneumoniae, P. aeruginosa, and P. mirabilis strains (MICs = In vivo, tigecycline (6.25 mg/kg twice daily for 5 days) decreases levels of C. difficile cytotoxin activity and spore formation in cecum and colon in a mouse model of C. difficile infection. Formulations containing tigecycline have been used in the treatment of a variety of bacterial infections.