Higenamine hydrochloride (Norcoclaurine hydrochloride) 是一种 β2-AR 激动剂，是东亚国家治疗心力衰竭的中药乌头的关键成分。Higenamine hydrochloride (Norcoclaurine hydrochloride) 具有抗凋亡作用。
货号:ajcx14488
CAS:11041-94-4
分子式:C16H18ClNO3
分子量：307.77
溶解度:DMSO: 100 mg/mL (324.92 mM); H2O: 10 mg/mL (32.49 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Higenamine hydrochloride (Norcoclaurine hydrochloride), a β2-AR agonist, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine hydrochloride (Norcoclaurine hydrochloride) has anti-apoptotic effects[1][2].

[1]. Wu MP, et al. Higenamine protects ischemia/reperfusion induced cardiac injury and myocyte apoptosis through activation of β2-AR/PI3K/AKT signaling pathway. Pharmacol Res. 2016 Feb;104:115-23. [2]. Lee SR, et al. Acute oral intake of a higenamine-based dietary supplement increases circulating free fatty acidsand energy expenditure in human subjects. Lipids Health Dis. 2013 Oct 21;12:148.