CAS NO: | 146554-87-2 |
包装: | 50mg, 100mg, 250mg |
规格: | ≥98% |
LY 290324 is an orally bioavailable, potent and selective cysteinyl leukotriene ((LTD4) receptor antagonist. In vitro, LY290324 was a potent and persistent antagonist of the contractile responses to LTD4 and LTE4 with pA2 values of 9.1 +/- 0.2 and 8.9 +/- 0.17 respectively. It is also effective in reducing antigen-induced bronchospasm in immunologically sensitised animals. References: Boot JR, Bond A, Thomas KH, O'Brien A, Gilmore J, Todd A. The pharmacology of LY290324 in the guinea-pig: an orally active, potent and selective cysteinyl leukotriene receptor antagonist. Eur J Pharmacol. 1993 Jan 26;231(1):83-9. PubMed PMID: 8383064.
纯度:≥98%
CAS:146554-87-2