(R)-UT-155(compound11)是一种选择性的、雄激素受体降解物(SARD)配体。活性低于S型异构体。
货号:ajcx12452
CAS:2031161-54-1
分子式:C20H15F4N3O2
分子量:405.35
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
(R)-UT-155 (compound 11) is a selective androgen receptor degrader (SARD) ligand. Less active than the S-isomer[1][2].
[1]. US20180360805. [2]. Ponnusamy S, et al. Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer. Cancer Res. 2017 Nov 15;77(22):6282-6298.