LY 186126 is a potent cGI-PDE inhibitor. It exhibit reversible, high affinity (Ka = 6 nM) binding to a single class of SaR binding sites. References: Ashikaga T, Robertson DW, Sportsman RJ, Strada SJ, Thompson WJ. Comparison of indolidan analog binding sites of drug antibody and sarcoplasmic reticulum with inhibition of cyclic AMP phosphodiesterase. J Recept Signal Transduct Res. 1996 Sep-Nov;16(5-6):315-37. PubMed PMID: 8968964.
纯度:≥98%
CAS:100644-00-6