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VPC-80051 racemate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
VPC-80051 racemate图片
规格:98%
分子量:301.29
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
VPC-80051 racemate 是一种 VPC-80051 外消旋体。VPC-80051是 hnRNP A1 剪接因子的原型抑制剂。
货号:ajcx36144
CAS:877969-69-2
分子式:C16H13F2N3O
分子量:301.29
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

VPC-80051 racemate is a racemate of VPC-80051. VPC-80051 is a prototype inhibitor of the hnRNP A1 splicing factor[1].

VPC-80051 interacts directly with hnRNP A1 RBD and reduces AR-V7 messenger levels in 22Rv1 CRPC cell line. hnRNP A1 is a multifunctional RNA-binding protein that regulates alternative pre-mRNA splicing, transcription, nucleocytoplasmic shuttling, miRNA processing, and telomere elongation maintenance, as well as translation of cellular transcripts both in physiological and pathological conditions[1].

[1]. Carabet LA, et al. Computer-Aided Discovery of Small Molecules Targeting the RNA Splicing Activity of hnRNP A1 in Castration-Resistant Prostate Cancer. Molecules. 2019;24(4):763. Published 2019 Feb 20.