R-(+)-Mono-desmethylsibutramine是Mono-desmethylsibutramine的R对映体。
货号:ajcx35820
CAS:229639-54-7
分子式:C16H24ClN
分子量：265.82
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

R-(+)-Mono-desmethylsibutramine is the R enantiomer of Mono-desmethylsibutramine.

Sibutramine, a monoamine reuptake inhibitor, is used as a racemate, for the treatment of obesity. It is converted in vivo mainly to two desmethyl active metabolites, mono-desmethylsibutramine (MDS) and di-desmethylsibutramine (DDS) [1].

[1]. Bae K, et al. Analysis of enantiomers of sibutramine and its metabolites in rat plasma by liquid chromatography-mass spectrometry using a chiral stationary-phase column. J Pharm Biomed Anal. 2009 Sep 8;50(2):267-70.