(Rac)-MRI-1867 是一种 CB1R/iNOS 双重靶向抑制剂,对 CB1R 作用的 Ki 值为 5.7 nM。(Rac)-MRI-1867 具有用于肝纤维化研究的潜力。
货号:ajcx35626
CAS:1610420-28-4
分子式:C25H21ClF3N5O2S
分子量:547.98
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
(Rac)-MRI-1867 (compound 6b) is a cannabinoid receptor type 1 (CB1R)/iNOS antagonist, with a Ki of 5.7 nM for CB1R. (Rac)-MRI-1867 is potential for the research of liver fibrosis[1].
[1]. Design, Synthesis, and Biological Evaluation of Novel, Non-Brain-Penetrant, Hybrid Cannabinoid CB 1 R Inverse Agonist/Inducible Nitric Oxide Synthase (iNOS) Inhibitors for the Treatment of Liver Fibrosis.