SHP389 是 SHP2 的变构抑制剂,其对 SHP2 和 p-ERK 的 IC50 值均为 36 nM。
货号:ajcx35194
CAS:2235394-90-6
分子式:C23H29ClN8O2
分子量:484.98
溶解度:DMSO : 100 mg/mL (206.19 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
SHP389 is an allosteric SHP2 inhibitor, with an IC50 of 36 nM for both SHP2 and p-ERK[1].
SHP389 modulates MAPK signaling in vivo[1].