Eliapixant (BAY 1817080) 是一种有效和选择性的 P2X3 受体拮抗剂，IC50 值为 8 nM。Eliapixant 可用于难治性慢性咳嗽的研究。
货号:ajcx34726
CAS:1948229-21-7
分子式:C22H21F3N4O3S
分子量：478.49
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough[1][2].

Eliapixant can be used for the research of coughs and diabetes complications[1].

[1]. Spinaci A, et, al. P2X3 Receptor Ligands: Structural Features and Potential Therapeutic Applications. Front Pharmacol. 2021 Apr 13;12:653561.
[2]. Morice A, et, al. Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough: a randomised, placebo-controlled, crossover phase 2a study. Eur Respir J. 2021 May 13;2004240.