A2B receptor antagonist 2 (compound 18) 是腺苷受体 A2B 的拮抗剂,其对rA1、rA2A 和 hA2BKi 值分别为2.30 μM、6.8 μM 和3.44 μM。
货号:ajcx34476
CAS:784-90-7
分子式:C12H15N5
分子量:229.28
溶解度:Methanol : 5 mg/mL (21.81 mM; ultrasonic and warming and heat to 60°C)|DMSO : 2 mg/mL (8.72 mM; ultrasonic and warming and heat to 60°C)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
A2B receptor antagonist 2 (compound 18) is an adenosine receptor A2B antagonist, with Ki values of 2.30 μM, 6.8 μM and 3.44 μM for rA1, rA2A and hA2B, respectively[1].
[1]. Thomas R Webb, et al. Quinazolines as adenosine receptor antagonists: SAR and selectivity for A2B receptors. Bioorg Med Chem. 2003 Jan 2;11(1):77-85.