ARV-471 是一种同类最优的,具有口服活性的雌激素受体 (ER) PROTAC 类降解剂。ARV-471 被开发用于乳腺癌的研究。
货号:ajcx34288
CAS:2229711-68-4
分子式:C45H49N5O4
分子量:723.9
溶解度:DMSO : 110 mg/mL (151.95 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
ARV-471 is a best-in-class, orally active estrogen receptor (ER) PROTAC degrader. ARV-471 is developed for the research of breast cancer[1].
[1]. John J. Flanagan, et al. ARV-471, an oral estrogen receptor PROTAC™ protein degrader for breast cancer. American Association for Cancer Research.2019. 79 (4): P5-04-18.