KRAS G12D inhibitor 1 (example 243) 是 KRAS G12D 的抑制剂,其对KRAS G12D 介导的 ERK 磷酸化的 IC50 值为0.8 nM。
货号:ajcx33306
CAS:2621928-43-4
分子式:C33H32F2N6O2
分子量:582.64
溶解度:DMSO : 55 mg/mL (94.40 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
KRAS G12D inhibitor 1 (example 243) is a KRAS G12D inhibitor, with an IC50 of 0.8 nM for KRAS G12D-mediated ERK phosphorylation[1].
[1]. WANG XIAOLUN (US), et al. KRAS G12D INHIBITORS. WO2021041671.