CAS NO: | 340021-17-2 |
规格: | ≥98% |
包装 | 价格(元) |
5mg | 电议 |
50mg | 电议 |
500mg | 电议 |
Tonapofylline, formerly known as BG9928, is a selective adenosine-1 receptor antagonist under development for the treatment of heart failure. Tonapofylline promotes natriuresis and diuresis, and may preserve glomerular filtration rate in patients with heart failure. Additionally, pilot data indicate that tonapofylline may be renoprotective in the setting of concomitant treatment with a loop-diuretic. Tonapofylline has natriuretic effects and is able to maintain renal function, which can be beneficial to patients with congestive heart failure. References: Li Z, Tenhoor C, Marbury T, Swan S, Zhu Y, Ticho B. Pharmacokinetics and pharmacodynamics of tonapofylline in subjects with severe renal impairment and in elderly subjects. Int J Clin Pharmacol Ther. 2011 Sep;49(9):563-70. PubMed PMID: 21888869.
纯度:≥98%
CAS:340021-17-2