(Rac)-3′-Hydroxysimvastatin是一种Simvastatin代谢物。Simvastatin是一种竞争性的HMG-CoA还原酶抑制剂,Ki值为0.2nM。
货号:ajcx29826
CAS:126313-98-2
分子式:C25H38O6
分子量:434.57
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
(Rac)-3′-Hydroxy simvastatin is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM[1][2].
[1]. Slater, E.E., et al. Mechanism of action and biological profile of HMG CoA reductase inhibitors. A new therapeutic alternative. Drugs, 1988. 36 Suppl 3: p. 72-82.