Meranzin是一种从传统中药Chaihu-Shugan-San(CSS)中的生物活性化合物。Meranzin从紫茉莉叶中分离出的，可以调节共有的α2-肾上腺素受体，并参与AMPA-ERK1/2-BDNF信号传导。Meranzin具有预防动脉粥样硬化和抑郁症合并症的潜力。
货号:ajcx29498
CAS:23971-42-8
分子式:C15H16O4
分子量：260.29
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Meranzin is an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS). Meranzin, isolated from leaves of Murraya exotica L., regulates the shared alpha 2-adrenoceptor and involves the AMPA-ERK1/2-BDNF signaling pathway. Meranzin has the potential for the prevention of the comorbidity of atherosclerosis and depression[1][2].

[1]. Lan Li, et al. Chaihu-Shugan-San and Absorbed Meranzin Hydrate Induce Anti-Atherosclerosis and Behavioral Improvements in High-Fat Diet ApoE -/- Mice via Anti-Inflammatory and BDNF-TrkB Pathway. Biomed Pharmacother. 2019 Jul;115:108893. [2]. Rongwei Yan, et al. Preparative Isolation and Purification of Hainanmurpanin, Meranzin, and Phebalosin From Leaves of Murraya Exotica L. Using Supercritical Fluid Extraction Combined With Consecutive High-Speed Countercurrent Chromatography. J Sep Sci. 2018 May;41(9):2092-2101.