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1,6-Hexanediol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
1,6-Hexanediol图片
包装:10g
规格:98%
市场价:712元
分子量:118.18

产品介绍
Tool for probing liquid-liquid phase separation
货号:ajcx27964
CAS:629-11-8
分子式:C6H14O2
分子量:118.18
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Widely used tool to probe liquid-liquid phase separation (LLPS) in cells. Disrupts hydrophobic interaction-induced phase separation assemblies both in vitro and in vivo. Dissolves LLPS condensates, such as P bodies, but not solid-like condensates, such as protein aggregates and cytoskeletal assemblies.Typically used as a 3-10% solution (w/v). Disrupts cellular structures in yeast and alters cellular morphology in HeLa cells.


Shan et al (2018) Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division. Nat.Commun. 9 737 PMID:29467404 |Wheeler et al (2016) Distinct stages in stress granule assembly and disassembly. Elife 5 e18413 PMID:27602576 |Kroschwald et al (2017) Hexanediol: a chemical probe to investigate the material properties of membrane-less compartments. Matters