LX-5 is a selective activator of the p38 mitogen-activated protein kinase (MAPK) pathway. LX-5 de-represses a subset of endogenous genes repressed by DNA methylation. References: Li X, Shang E, Dong Q, Li Y, Zhang J, Xu S, Zhao Z, Shao W, Lv C, Zheng Y, Wang H, Lei X, Zhu B, Zhang Z. Small molecules capable of activating DNA methylation-repressed genes targeted by the p38 mitogen-activated protein kinase pathway. J Biol Chem. 2018 May 11;293(19):7423-7436. doi: 10.1074/jbc.RA117.000757. Epub 2018 Mar 20. PubMed PMID: 29559556; PubMed Central PMCID: PMC5950019.
纯度:≥98%
CAS:377054-82-5