包装: | 100ug |
规格: | 98% |
市场价: | 817元 |
分子量: | 453.1 |
Background:
Heptadecanoyl-L-carnitine-d3is intended for use as an analytical standard for the quantification of heptadecanoyl-L-carnitine by GC- or LC-MS. Heptadecanoyl-L-carnitine is a long-chain acylcarnitine composed of heptadecanoic acid and L-carnitine . Levels of heptadecanoyl-L-carnitine are increased in dried blood spots from neonates with propionic or methylmalonic acidemias, inborn errors of metabolism characterized by a deficiency in the activity of propionyl-CoA carboxylase or L-methylmaolnyl-CoA mutase or its cofactor 5-deoxyadenosylcobalamin, respectively.1
1.Malvagia, S., Haynes, C.A., Grisotto, L., et al.Heptadecanoylcarnitine (C17) a novel candidate biomarker for propionic and methylmalonic acidemias during expanded newborn screeningClin. Chim. Acta450342-348(2015)