12-羟基硬脂酸是一种结构简单且具有成本效益的低分子量有机凝胶剂，其金属盐和衍生物在许多重要应用中发挥作用。
货号:ajcx25582
CAS:106-14-9
分子式:C18H36O3
分子量：300.5
溶解度:DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

12-hydroxy Stearic acid is a hydroxy fatty acid produced by the hydrogenation of ricinoleic acid .¹It is a low molecular weight gelator that self-assembles to form organogels.²Administration of paclitaxel in 12-hydroxy stearic acid-containing gel nanocarriers enhances tumor growth suppression in an H22 murine hepatocellular carcinoma model.³Formulations containing 12-hydroxy stearic acid have been used in cosmetic products as emollients.

1.Fameau, A.-L., and Rogers, M.A.The curious case of 12-hydroxystearic acid — the Dr. Jekyll & Mr. Hyde of molecular gelatorsCurr. Opin. Colloid Interface Sci.4568-82(2020) 2.Burkhardt, M., Noirez, L., and Gradzielski, M.Organogels based on 12-hydroxy stearic acid as a leitmotif: Dependence of gelation properties on chemical modificationsJ. Colloid Interface Sci.466369-376(2016) 3.He, W., Lv, Y., Zhao, Y., et al.Core-shell structured gel-nanocarriers for sustained drug release and enhanced antitumor effectInt. J. Pharm.484(1-2)163-171(2015)