A monolignol with anti-inflammatory and antinociceptive activities
货号:ajcx25202
CAS:537-33-7
分子式:C11H14O4
分子量：210.2
溶解度:DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 1 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Sinapyl alcohol is a monolignol and an aglycone form of syringin that has been found inPopulus albaand has anti-inflammatory and antinociceptive activities.^1,2It is a precursor in the biosynthesis of lignin.¹Sinapyl alcohol (50, 100, and 200 µM) reduces LPS-induced production of nitrite, prostaglandin E₂, and TNF-α in RAW 264.7 cells.²Sinapyl alcohol (20 and 30 mg/kg) inhibits acetic acid-induced writhing and increases the latency to paw licking in the hot plate test in mice.

1.Shigeto, J., Ueda, Y., Sasaki, S., et al.Enzymatic activities for lignin monomer intermediates highlight the biosynthetic pathway of syringyl monomers in Robinia pseudoacaciaJ. Plant Res.130(1)203-210(2017) 2.Choi, J., Shin, K.-M., Park, H.-J., et al.Anti-inflammatory and antinociceptive effects of sinapyl alcohol and its glucoside syringinPlanta Med.70(11)1027-1032(2004)