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Ofloxacin-d8(hydrochloride)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ofloxacin-d8(hydrochloride)图片
规格:98%
分子量:405.9
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
C18H12D8FN3O4•HCl
货号:ajcx24282
CAS:N/A
分子式:C18H12D8FN3O4•HCl
分子量:405.9
溶解度:DMSO: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Ofloxacin-d8is intended for use as an internal standard for the quantification of ofloxacin by GC- or LC-MS. Ofloxacin is a broad-spectrum fluoroquinolone antibiotic that prevents supercoiling of bacterial chromosomes by DNA gyrase.1,2It is active against Gram-positive and Gram-negative bacteria with MIC90s ranging from 0.39 to 3.13 μg/ml for clinical isolates ofS. aureus,S. epidermidis,S. pyogenes, andS. faecalisand ≤0.78 μg/ml forN. gonorrhoeaeand various species of Enterobacteriaceae. Ofloxacin is activein vivo, with ED50values ranging from 0.7 to 75.1 mg/kg in infected mice. Formulations containing ofloxacin have been used to treat urinary tract infections, gonorrhea, prostatitis, and gastroenteritis.


1.Sato, K., Matsuura, Y., Inoue, M., et al.In vitro and in vivo activity of DL-8280, a new oxazine derivativeAntimicrob. Agents and Chemother.22(4)548-553(1982) 2.Smith, J.T.The mode of action of 4-quinolones and possible mechanisms of resistanceJ. Antimicrob. Chemother.18 (Suppl. D)21-29(1986)