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Ac-DEVD-CMK(trifluoroacetate salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ac-DEVD-CMK(trifluoroacetate salt)图片
规格:98%
分子量:551
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
C21H31ClN4O11•XCF3COOH
货号:ajcx24028
CAS:N/A
分子式:C21H31ClN4O11•XCF3COOH
分子量:551
溶解度:DMSO: 50 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Ac-DEVD-CMK is a cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, -7, -8, and -10.1,2,3It is commonly used at concentrations up to 100 μM to examine the role of caspase-3-dependent apoptosis in biological systems.4,1


1.Mocanu, M.M., Baxter, G.F., and Yellon, D.M.Caspase inhibition and limitation of myocardial infarct size: Protection against lethal reperfusion injuryBritish Journal of Pharmacology130(2)197-200(2000) 2.Schrantz, N., Blanchard, D.A., Mitenne, F., et al.Manganese induces apoptosis of human B cells: Caspase-dependent cell death blocked by Bcl-2Cell Death and Differentiation6(5)445-453(1999) 3.Thornberry, N.A., and Lazebnik, Y.Caspases: Enemies withinScience2811312-1316(1998) 4.Zhang, Y., Wang, H., Li, J., et al.Peroxynitrite-induced neuronal apoptosis is mediated by intracellular zinc release and 12-lipoxygenase activationJournal of Neuroscience24(47)10616-10627(2004)