An internal standard for the quantification of arachidonic acid
货号:ajcx21704
CAS:123167-26-0
分子式:C20H27D5O2
分子量：309.5
溶解度:0.1 M Na2CO3: 1 mg/ml,DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 50 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Arachidonic acid-d₅is intended for use as an internal standard for the quantification of arachidonic acid by GC- or LC-MS. Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways.¹Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are all important aspects of cell signaling and inflammation.²

1.Nixon, A.B., Greene, D.G., and Wykle, R.L.Comparison of acceptor and donor substrates in the CoA-independent transacylase reaction in human neutrophilsBiochim. Biophys. Acta.1300(3)187-196(1996) 2.Burgoyne, R.D., and Morgan, A.The control of free arachidonic acid levelsTrends Biochem. Sci.15(10)365-366(1990)