A neuropeptide with diverse biological activities
货号:ajcx21702
CAS:N/A
分子式:C20H21D11O2
分子量：315.5
溶解度:0.1 M Na2CO3: 1.7 mg/ml,DMF: >100 mg/ml,DMSO: >100 mg/ml,Ethanol: Miscible
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Arachidonic acid-d₁₁contains 11 deuterium atoms at the 16, 16, 17, 17, 18, 18, 19, 19, 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of arachidonic acid by GC-or LC-mass spectrometry. Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways.¹Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are all important aspects of cell signaling and inflammation.²

1.Nixon, A.B., Greene, D.G., and Wykle, R.L.Comparison of acceptor and donor substrates in the CoA-independent transacylase reaction in human neutrophilsBiochim. Biophys. Acta.1300(3)187-196(1996) 2.Burgoyne, R.D., and Morgan, A.The control of free arachidonic acid levelsTrends Biochem. Sci.15(10)365-366(1990)