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Histone H3K27Me1(21-44)-GK-biotin(trifluoroacetate salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Histone H3K27Me1(21-44)-GK-biotin(trifluoroacetate salt)图片
包装:250ug
规格:98%
市场价:2918元
分子量:2931.5

产品介绍
Histone H3K27Me1 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and H3.2 sequences.
货号:ajcx18564
CAS:N/A
分子式:C128H216N44O33S•XCF3COOH
分子量:2931.5
溶解度:Water: 1 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Histone H3K27Me1 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and H3.2 sequences. It is monomethylated at lysine 27 and biotinylated via a C-terminal GK linker. Monomethylation of histone H3 at lysine 27 is associated with actively transcribed genes and positively correlates with H3K36 trimethylation. Levels of H3K27Me1 are increased in tumor tissue isolated from patients with metastatic hormone-na?ve and castration-resistant prostate cancer. Histone H3K27Me1 (21-44)-GK-biotin has been used in a high-throughput screen for inhibitors of the histone demethylase jumonji AT-rich interactive domain 1B (JARID1B).