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D-myo-Inositol-2,4,5-triphosphate(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
D-myo-Inositol-2,4,5-triphosphate(sodium salt)图片
规格:98%
分子量:486
包装与价格:
包装价格(元)
100ug电议
500ug电议
1mg电议

产品介绍
The inositol phosphates (InsP) play a critical role as small, soluble second messengers in the transmission of cellular signals.
货号:ajcx18378
CAS:N/A
分子式:C6H12O15P3•3Na
分子量:486
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:现货

Background:

The inositol phosphates (InsP) play a critical role as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, D-myo-Inositol-2,4,5-triphosphate (sodium salt) (Ins(1,4,5)P3), more commonly referred to as IP3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(2,4,5)P3 is a metabolically stable analog of Ins(1,4,5)P3 that is commonly used to study Ca2+ signaling pathways. Ins(2,4,5)P3 acts as a partial agonist at rat hepatic IP3 receptors, exhibiting 65% of the maximal Ca2+ response obtained with Ins(1,4,5)P3.