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D-myo-Inositol-1,3,4-triphosphate(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
D-myo-Inositol-1,3,4-triphosphate(sodium salt)图片
规格:98%
分子量:486
包装与价格:
包装价格(元)
100ug电议
500ug电议
1mg电议

产品介绍
The inositol phosphates play a critical role as small, soluble second messengers in transmission of cellular signals.
货号:ajcx18360
CAS:N/A
分子式:C6H12O15P3•3Na
分子量:486
溶解度:PBS pH 7.2: >50 mg/ml (from D-myo-Inositol
纯度:98%
存储:Store at -20°C
库存:现货

Background:

The inositol phosphates play a critical role as small, soluble second messengers in transmission of cellular signals. D-myo-Inositol-1,3,4-triphosphate (Ins(1,3,4)-P3) is one of several different inositol oligophosphate isomers implicated in signal transduction. Ins(1,3,4)-P3 acts through the inhibition of Ins(3,4,5,6)-P4 kinase activity to increase the cellular level of Ins(3,4,5,6)-P4 and thus inhibit calcium-activated chloride channels. The levels of Ins(1,3,4)-P3 are in turn regulated by the levels of cytosolic free calcium. The receptor-mediated activation of phospholipase C (PLC) can be seen as the initiating event in this cascade, since PLC generates Ins(1,4,5)-P3 which releases calcium from intracellular storage reservoirs, leading to a dramatic but transient increase in the cytosolic concentration of free calcium.