| 包装: | 100ug |
| 规格: | 98% |
| 市场价: | 3689元 |
| 分子量: | 3371 |
Background:
Defensin HNP-2 is a peptide with antimicrobial properties that is secreted by human polymorphonuclear leukocytes (PMNs). It induces 26.2 and 43.5% lysis of mammalian cells at concentrations of 25 and 100 μg/ml, respectively. It also completely inhibits secretion of the exotoxin superantigen TSS toxin-1 (TSST-1) from S. aureus at a concentration of 5 ng/ml and inhibits infection of McCoy cells by C. trachomatis elementary bodies (EBs). Defensin HNP-2 binds to recombinant HIV-1 envelope glycoprotein gp120 and human CD4 (Kds = 8 and 15.8 nM, respectively). It also induces permeabilization of large unilamellar vesicles (LUVs) formed from 1-palmitoyl-2-oleoyl-sn-glycero-3-PG .
m.cnreagent.com