Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.
货号:ajcx17818
CAS:N/A
分子式:C27H37F3O5
分子量：498.6
溶解度:DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 50 mg/ml,Ethanol:PBS(pH 7.2) (1:5): 0.2 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor PGF2α is an analog of PGF2α that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoromethylphenyl trinor PGF2α isopropyl ester is a lipophilic analog of 17-trifluoromethylphenyl trinor PGF2α. Isopropyl esters of PGs can serve as prodrugs, as they can be efficiently hydrolyzed in certain tissues to generate the bioactive free acid.