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10(S)-PAHSA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
10(S)-PAHSA图片
规格:98%
分子量:538.9
包装与价格:
包装价格(元)
500ug电议
1mg电议

产品介绍
10(S)-PAHSA is a stereoisomer of 10-PAHSA, an endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).
货号:ajcx17572
CAS:N/A
分子式:C34H66O4
分子量:538.9
溶解度:DMF: 20 mg/ml,DMSO: 15 mg/ml,Ethanol: 20 mg/ml,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

10(S)-PAHSA is a stereoisomer of 10-PAHSA , an endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs). It is a FAHFA in which palmitic acid is esterified to 10-hydroxy stearic acid. Among the FAHFA family members, PAHSAs are the most abundant in the adipose tissue of glucose tolerant AG4OX mice, which overexpress the Glut4 glucose transporter specifically in adipose tissue. A study using synthesized (R)- and (S)- stereoisomers of 9-PAHSA reported that the 9(R)-PAHSA is the predominant form that accumulates in adipose tissues in vivo. Also, cell lines favor the production of 9(R)-PAHSA and carboxyl ester lipase selectively hydrolyzes 9(S)-PAHSA .The use of this optically-active FAHFA product (the "Product") is covered by U.S. Patent No. 10,240,025 and corresponding foreign counterpart applications.