DM4-SMCC 是一种抗体-药物偶联物 (drug-linker conjugate for ADC)，具有抗肿瘤活性，由抗微管抑制剂 DM4 和不可切割的 SMCC 连接而成。
货号:ajcx14846
CAS:1228105-52-9
分子式:C54H72ClN5O16S
分子量：1114.69
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

DM4-SMCC is a drug-linker conjugate for ADC with antitumor activity by using DM4 (an antitubulin agent), linked via the non-cleavable SMCC linker[1].

[1]. Singh R, et al. A New Triglycyl Peptide Linker for Antibody-Drug Conjugates (ADCs) with Improved TargetedKilling of Cancer Cells. Mol Cancer Ther. 2016 Jun;15(6):1311-20.