BI-167107 是一种高亲和力的 β2 肾上腺素能受体 (β2AR) 完全激动剂，与 β2 肾上腺素能受体 (β2AR) 结合，解离常数 Kd 为 84 pM。
货号:ajcx14714
CAS:1202235-68-4
分子式:C21H26N2O4
分子量：370.44
溶解度:DMSO: 75 mg/mL (202.46 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

BI-167107 is a high affinity, full agonist that binds to the β2 adrenergic receptor (β2AR) with a dissociation constant Kd of 84 pM[1].

Compared to other βAR ligands, BI-167107 displays nanomolar affinities and slow off-rates[1].

[1]. Rasmussen SG, et al. Structure of a nanobody-stabilized active state of the β(2) adrenoceptor. Nature. 2011 Jan 13;469(7329):175-80.